Countries around the world have closed their external borders in a bid to control and isolate COVID-19. In these circumstances, criminals are finding new ways to abuse the vulnerability of irregular migrants wishing to enter or travel across Europe and those financially struggling, victimised in labour or sexual exploitation schemes. The new report of the European Migrant Smuggling centre (EMSC) at Europol looks back at the operations supported in 2019 and the intelligence gathered to draw the possible evolution of these crime areas in the upcoming months. A clear outlook of the potential developments would prepare a more effective response to these life-threatening criminal activities.